According to the Office of Human Research Protections, _____ refers to unexpected events that likely occur as a result of participation in the research.

The term that aligns with the description provided in the question is "unanticipated problems." This term is specifically defined by the Office of Human Research Protections (OHRP) to encompass unexpected events that occur during research, which can present risks to participants that were not previously identified. These problems could affect participant safety or the integrity of the research.

In the context of research ethics and oversight, identifying and reporting these unanticipated problems is crucial for ensuring the protection of human subjects and maintaining ethical standards in research practices. The recognition of such issues allows researchers and oversight bodies to take appropriate actions, such as modifying protocols or informing participants, thereby mitigating harm and improving the safety of future research activities.

The other terms mentioned do not adequately capture this specific definition. "Unanticipated protocols" implies changes or guidelines that were not planned but lacks the direct connection to unexpected events affecting research participants. "Adverse consequences" suggests negative outcomes but does not specifically refer to their unexpected nature in the context of research. Similarly, "adverse experiences" indicates negative experiences but does not emphasize their unanticipated aspect in relation to research participation. Therefore, "unanticipated problems" is the most accurate choice given the context and definitions provided by the OHRP.